Textbook of Neonatology

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The normal healthy fetus receives a constant influx of glucose from the mother. This constant influx provides for basal fetal metabolism. The normal fetoplacental glucose utilization rate is 5 to 6 mg/kg/min. After 27 weeks gestation, this glucose influx also provides for convertion into glycogen, which is deposited mainly in the liver. The fetal glucose levels are maintained by transport of ma...

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The term, Hypoplastic Left Heart Syndrome (HLHS), initially proposed by Noonan and Nadas,8 describes a diminutive left ventricle with underdevelopment of mitral and aortic valves. A patent foramen ovale or an atrial septal defect is usually present. The ventricular septum is usually intact. A large patent ductus arteriosus supplies blood to the systemic circulation. Coarctation of the aorta is ...

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Data from four multicenter trials1-4 indicates that hypothermia is effective in diminishing brain injury in some neonates with moderate to severe hypoxic-ischemic encephalopathy (HIE). Currently, hypothermia is emerging as a standard of care for certain neonates with HIE. Meta-analysis suggests the therapy may prevent long-term neurologic deficits in one neonate for every 8 treated.5 Since hypo...

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Various estimates suggest that potentially life-threatening congenital heart disease is present in approximately 1:1,000 births1-5 (Table 1). Unfortunately this heart disease will go unrecognized in some neonates until symptoms develop. These delayed or missed diagnoses can result in both disability and death. The incidence of a missed diagnosis of critical congenital heart disease can be defin...

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This study examined amplitude integrated electroencephalogram (aEEG) characteristics in term neonates undergoing treatment for Neonatal Abstinence Syndrome (NAS). Twenty mothers consented to participate and eight infants with an estimated gestational age ≥37 weeks and undergoing treatment for NAS were placed on aEEG for the first 72 hours of life and then, when possible, for 48 hours every week...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1987

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.62.1.104